Comparing the blood gardenal concentration with clinical manifestations and the results of treating the acute gardenal-poisoned patients

55 gardenal-poisoned patients were measured the drug’s blood levels to compare with their clinical manifestations and select appropriate treatment methods. The mean value was 36.87mg/l. The patients with the blood gardenal levels equal to or less than 60mg/l usually had first or second-stage coma, mild respiratory failure (if any), and fewer severe complications. This group of patients only required simple measures such as gastric lavage, the use of activated charcoal, enhanced diuresis and urine alkalization. Whereas the patients with the levels more than 60mg/l commonly suffered from third or fourth-degree coma, severe to life-threatening respiratory failure, hypotension and other severe complications. They not only needed simple curative methods but also mechanical ventilation and hemodialysis. the hemodialysis could reduce the blood gardenal concentration up to 665 for each intervention period. Owing to this extracorporeal technique for the removal of toxins, the duration of mechanical ventilation, enhanced diuresis, urine alkalization as well as the necessary amount of bicarbonate was decreased remarkably.

Evaluation of the levels of auto-PEEP in the patients with acute respiratory failure required mechanical ventilation

At the intensive care unit of Bachmai hospital, in 27 patients with acute pulmonary deficiency syndrome of different causes, who were undergone invasive artificial ventilation, auto-PEEP was assessed. Patients with ARDS had got auto-PEEP of 9,15±4cm Hg, with COPD 12±2,8cm H2O, with asthma crisis 20,4±7,2cm H2O. The use of specific chemotherapies and setting PEEP equal to haft of auto-PEEP to treat the patients with ARDS and COPD had minished the value of auto-PEEP to 4,67±3,7cm H2O in ARDS, 7±2,31 in COPD and 9,71± 1,67 in asthma; blood vapor level was improved also

Nerestoxin poisoning

In 2002-2004 year period, at Bach Mai Hospital, 6 intoxicated victims aged 14-41 were admitted (3 males, 3 females). They attempted to suicide and hospitalized 15-60 min. after use the toxic with the symptoms of gastro-enteritis (vomit even vomit with blood), abdomen pain, diarrhoea, purpurae and systenic edema, circulation volume reduced, high blood pressure, tachycardia, 3 victims who consumed 7-10g recovered but 3 who consumed > 20g died 24 hours after hospitalization

Evaluation of the levels of auto-PEEP in the patients with acute respiratory failure required mechanical ventilation

We have studied 27 patients on medical ventilation in whom we measured auto-PEEP by means of end expiratory airway occlusion. Four patients with ARDS had 10.25  2.05 cm H2O of auto PEEP. Six patients with COPD had 12.83  4.98 cm H2O of auto PEEP. Seven patients with acute severe asthma had 20.29  7.21 cm H2O of auto PEEP. Ten patients with neuromuscular disease had 5.2  4.07 cm H2O of auto PEEP. PEEP was set equal to half the auto-PEEP to treat patients with ARDS, COPD and acute severe asthma. We have show that the value of auto PEEP fell to 4.67  3.7 cm H2O in patient with ARDS, to 7  2.31 in patient of COPD and to 9.71  1.67 in patients of asthma. PEEP 50% of auto-PEEP is safe and does not worsen pulmonary hyperinflation

B-type natriuretic peptide levels in the patients with hypertensive heart failure

In 32 hypertensive heart failure patients (HHF group) including 19 male, 13 female, aged 60.3710.25 and 10 patients without HHF: 5 male, 5 female, aged 69.4  1.2, plasma BNP level in HHF group was 568.02  473.86 pg/ml and in without HHF group was 13.61  13.60 pg/ml. For HHF patients of degree I-IV, the sensitivity was 78%, and the specificity was 100% and for who of degree II-IV, sensitivity 92% and specificity 100%.